Differentiation of human induced pluripotent stem cells to mature functional Purkinje neurons

Differentiation of human induced pluripotent stem cells to mature functional Purkinje neurons

It remains a challenge to differentiate human induced pluripotent stem cells (iPSCs) or embryonic stem (ES) cells to Purkinje cells. In this study, we derived iPSCs from human fibroblasts and directed the specification of iPSCs first to Purkinje progenitors, by adding Fgf2 and insulin to the embryoi...

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Bibliographic Details
Main Authors: Wang, Shuyan, Wang, Bin, Pan, Na, Fu, Linlin, Wang, Chaodong, Song, Gongru, An, Jing, Liu, Zhongfeng, Zhu, Wanwan, Guan, Yunqian, Xu, Zhi-Qing David, Chan, Piu, Chen, Zhiguo, Zhang, Y. Alex
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363833/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363833/

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