A High Excision Potential of TALENs for Integrated DNA of HIV-Based Lentiviral Vector

DNA-editing technology has made it possible to rewrite genetic information in living cells. Human immunodeficiency virus (HIV) provirus, an integrated form of viral complementary DNA in host chromosomes, could be a potential target for this technology. We recently reported that HIV proviral DNA coul...

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Bibliographic Details
Main Authors: Ebina, Hirotaka, Kanemura, Yuka, Misawa, Naoko, Sakuma, Tetsushi, Kobayashi, Tomoko, Yamamoto, Takashi, Koyanagi, Yoshio
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363575/