Oxcarbazepine-loaded polymeric nanoparticles: development and permeability studies across in vitro models of the blood–brain barrier and human placental trophoblast
Encapsulation of antiepileptic drugs (AEDs) into nanoparticles may offer promise for treating pregnant women with epilepsy by improving brain delivery and limiting the transplacental permeability of AEDs to avoid fetal exposure and its consequent undesirable adverse effects. Oxcarbazepine-loaded nan...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362902/ |