The Long Pentraxin PTX3 Promotes Fibrocyte Differentiation
Monocyte-derived, fibroblast-like cells called fibrocytes are associated with fibrotic lesions. The plasma protein serum amyloid P component (SAP; also known as pentraxin-2, PTX2) inhibits fibrocyte differentiation in vitro, and injections of SAP inhibit fibrosis in vivo. SAP is a member of the pent...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361553/ |