Actin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles

In many secretory cells actin and myosin are specifically recruited to the surface of secretory granules following their fusion with the plasma membrane. Actomyosin-dependent compression of fused granules is essential to promote active extrusion of cargo. However, little is known about molecular mec...

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Bibliographic Details
Main Authors: Miklavc, Pika, Ehinger, Konstantin, Sultan, Ayesha, Felder, Tatiana, Paul, Patrick, Gottschalk, Kay-Eberhard, Frick, Manfred
Format: Online
Language:English
Published: The Company of Biologists 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359923/