Burden of disease variants in participants of the long life family Study

Case control studies of nonagenarians and centenarians provide evidence that long-lived individuals do not differ in the rate of disease associated variants compared to population controls. These results suggest that an enrichment of novel protective variants, rather than a lack of disease associate...

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Bibliographic Details
Main Authors: Stevenson, Meredith, Bae, Harold, Schupf, Nicole, Andersen, Stacy, Zhang, Qunyuan, Perls, Thomas, Sebastiani, Paola
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359694/