Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells

Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells

Atypical teratoid/rhabdoid tumor (ATRT) is a malignant pediatric brain tumor with great recurrence after complete surgery and chemotherapy. Here, we demonstrate that cisplatin treatment selects not only for resistance but also for a more oncogenic phenotype characterized by high self-renewal and inv...

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Bibliographic Details
Main Authors: Liu, Wei-Hsiu, Chen, Ming-Teh, Wang, Mong-Lien, Lee, Yi-Yen, Chiou, Guang-Yuh, Chien, Chian-Shiu, Huang, Pin-I, Chen, Yi-Wei, Huang, Ming-Chao, Chiou, Shih-Hwa, Shih, Yang-Hsin, Ma, Hsin-I
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359329/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359329/

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