Paths to a malaria vaccine illuminated by parasite genomics

•Discovery of vaccine candidate antigens by parasite genome sequence analyses.•Genetic crosses, linkage group selection, and functional studies on parasites.•Characterizing developmental and epigenetic variation alongside allelic polymorphism.•Selection by naturally acquired immune responses helps t...

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Bibliographic Details
Main Author: Conway, David J.
Format: Online
Language:English
Published: Elsevier Trends Journals 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359294/