P62 Regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis

Resveratrol is a potential polyphenol drug used in cancer treatment. We examined the relationship between autophagy and apoptosis in RSV-treated non-small lung adenocarcinoma A549 cells. Resveratrol treatment increased autophagy and autophagy-mediated degradation of P62. Immunocytochemistry revealed...

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Bibliographic Details
Main Authors: Zhang, Jun, Ma, Ke, Qi, Tingting, Wei, Xiaoning, Zhang, Qing, Li, Guanwu, Chiu, Jen-Fu
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359255/