Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients

Obesity is linked to increased incidence of endometrioid endometrial cancer (EEC) and complex atypical hyperplasia (CAH). We here explore pattern and sequence of molecular alterations characterizing endometrial carcinogenesis in general and related to body mass index (BMI), to improve diagnostic str...

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Bibliographic Details
Main Authors: Berg, Anna, Hoivik, Erling A., Mjøs, Siv, Holst, Frederik, Werner, Henrica M. J., Tangen, Ingvild L., Taylor-Weiner, Amaro, Gibson, William J., Kusonmano, Kanthida, Wik, Elisabeth, Trovik, Jone, Halle, Mari K., Øyan, Anne M., Kalland, Karl-Henning, Cherniack, Andrew D., Beroukhim, Rameen, Stefansson, Ingunn, Mills, Gordon B., Krakstad, Camilla, Salvesen, Helga B.
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359236/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359236/

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