Reciprocal activation between IL-6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of non-small cell lung cancer cells

Reciprocal activation between IL-6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of non-small cell lung cancer cells

Inflammatory cytokines and oxidative stress are two critical mediators in inflammation-associated cancer. Interleukin-6 (IL-6) is one of the most critical tumor-promoting cytokines in non-small cell lung cancer (NSCLC). In our recent study, we confirmed that NADPH oxidase 4 (NOX4), an important sour...

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Bibliographic Details
Main Authors: Li, Juan, Lan, Tian, Zhang, Cuixiang, Zeng, Cheng, Hou, Jincai, Yang, Zhicheng, Zhang, Min, Liu, Jianxun, Liu, Bing
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359215/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359215/

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