Glycan Engagement Dictates Hydrocephalus Induction by Serotype 1 Reovirus

Receptors expressed on the host cell surface adhere viruses to target cells and serve as determinants of viral tropism. Several viruses bind cell surface glycans to facilitate entry, but the contribution of specific glycan moieties to viral disease is incompletely understood. Reovirus provides a tra...

Full description

Bibliographic Details
Main Authors: Stencel-Baerenwald, Jennifer, Reiss, Kerstin, Blaum, Bärbel S., Colvin, Daniel, Li, Xiao-Nan, Abel, Ty, Boyd, Kelli, Stehle, Thilo, Dermody, Terence S.
Format: Online
Language:English
Published: American Society of Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358001/