Clinical Therapy Using iPSCs: Hopes and Challenges

Induced pluripotent stem cells (iPSCs) are generated by ectopic expression of defined transcription factors in somatic cells. They can undergo unlimited self-renewal and maintain the embryonic stem cells (ESCs)-like ability to differentiate into all three germ layers. iPSCs can potentially provide u...

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Bibliographic Details
Main Authors: Lu, Xiao, Zhao, Tongbiao
Format: Online
Language:English
Published: Elsevier 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357821/