Development of an oral push–pull osmotic pump of fenofibrate-loaded mesoporous silica nanoparticles

In this study, mesoporous silica nanoparticles (MSNs) were used to prepare an oral push–pull osmotic pump. Fenofibrate, the selected model drug, was firstly loaded into the MSNs, followed by a suspending agent consisting of a drug layer of push–pull osmotic pump. Fenofibrate-loaded MSNs were charact...

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Bibliographic Details
Main Authors: Zhao, Zongzhe, Wu, Chao, Zhao, Ying, Hao, Yanna, Liu, Ying, Zhao, Wenming
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356664/