Metabolic and Tissue-Specific Regulation of Acyl-CoA Metabolism

Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ligation of a fatty acid to Coenzyme A mediated by a large family of acyl-CoA synthetases (ACS). Conversely, acyl-CoAs can be hydrolyzed by a family of acyl-CoA thioesterases (ACOT). Here, we have determined...

Full description

Bibliographic Details
Main Authors: Ellis, Jessica M., Bowman, Caitlyn E., Wolfgang, Michael J.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356623/