BAD-mediated apoptotic pathway is associated with human cancer development

The malignant transformation of normal cells is caused in part by aberrant gene expression disrupting the regulation of cell proliferation, apoptosis, senescence and DNA repair. Evidence suggests that the Bcl-2 antagonist of cell death (BAD)-mediated apoptotic pathway influences cancer chemoresistan...

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Bibliographic Details
Main Authors: STICKLES, XIAOMANG B, MARCHION, DOUGLAS C, BICAKU, ELONA, SAWAH, ENTIDHAR AL, ABBASI, FOROUGH, XIONG, YIN, ZGHEIB, NADIM BOU, BOAC, BERNADETTE M, ORR, BRIAN C, JUDSON, PATRICIA L, BERRY, AMY, HAKAM, ARDESHIR, WENHAM, ROBERT M, APTE, SACHIN M, BERGLUND, ANDERS E, LANCASTER, JOHNATHAN M
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356438/