Effects of targeted phosphorylation site mutations in the DNA-PKcs phosphorylation domain on low and high LET radiation sensitivity

Effects of targeted phosphorylation site mutations in the DNA-PKcs phosphorylation domain on low and high LET radiation sensitivity

The present study investigated the effect of targeted mutations in the DNA-dependent protein kinase catalytic subunit and phosphorylation domains on the survival of cells in response to different qualities of ionizing radiation. Mutated Chinese hamster ovary V3 cells were exposed to 500 MeV/nucleon...

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Bibliographic Details
Main Authors: CARTWRIGHT, IAN M., BELL, JUSTIN J., MAEDA, JUNKO, GENET, MATTHEW D., ROMERO, ASHLEY, FUJII, YOSHIHIRO, FUJIMORI, AKIRA, KITAMUTA, HISASHI, KAMADA, TADASHI, CHEN, DAVID J., KATO, TAKAMITSU A.
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356358/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356358/

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