Modeling the Interaction between Quinolinate and the Receptor for Advanced Glycation End Products (RAGE): Relevance for Early Neuropathological Processes

The receptor for advanced glycation end products (RAGE) is a pattern-recognition receptor involved in neurodegenerative and inflammatory disorders. RAGE induces cellular signaling upon binding to a variety of ligands. Evidence suggests that RAGE up-regulation is involved in quinolinate (QUIN)-induce...

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Bibliographic Details
Main Authors: Serratos, Iris N., Castellanos, Pilar, Pastor, Nina, Millán-Pacheco, César, Rembao, Daniel, Pérez-Montfort, Ruy, Cabrera, Nallely, Reyes-Espinosa, Francisco, Díaz-Garrido, Paulina, López-Macay, Ambar, Martínez-Flores, Karina, López-Reyes, Alberto, Sánchez-García, Aurora, Cuevas, Elvis, Santamaria, Abel
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354912/