Soluble Interleukin-15 Complexes Are Generated In Vivo by Type I Interferon Dependent and Independent Pathways
Interleukin (IL)-15 associates with IL-15Rα on the cell surface where it can be cleaved into soluble cytokine/receptor complexes that have the potential to stimulate CD8 T cells and NK cells. Unfortunately, little is known about the in vivo production of soluble IL-15Rα/IL-15 complexes (sIL-15 compl...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354909/ |