Fatty Acid Elongase 7 Catalyzes the Lipidome Remodeling Essential for Human Cytomegalovirus Replication
Human cytomegalovirus (HCMV) infection rewires host cell metabolism, up-regulating flux from glucose into acetyl-CoA to feed fatty acid metabolism, with saturated very long-chain fatty acids (VLFCA) required for production of infectious virion progeny. The human genome encodes seven elongase enzymes...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354725/ |