Role of high-mobility group box-1 in myocardial ischemia/reperfusion injury and the effect of ethyl pyruvate
High-mobility group box-1 (HMGB1) acts as a proinflammatory cytokine that triggers and amplifies the inflammation cascade following ischemia/reperfusion (I/R). Ethyl pyruvate (EP) has been reported to inhibit HMGB1 release in several I/R models. This study was designed to investigate the potential r...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
D.A. Spandidos
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353799/ |