A High-Throughput In Vitro Drug Screen in a Genetically Engineered Mouse Model of Diffuse Intrinsic Pontine Glioma Identifies BMS-754807 as a Promising Therapeutic Agent

A High-Throughput In Vitro Drug Screen in a Genetically Engineered Mouse Model of Diffuse Intrinsic Pontine Glioma Identifies BMS-754807 as a Promising Therapeutic Agent

Diffuse intrinsic pontine gliomas (DIPGs) represent a particularly lethal type of pediatric brain cancer with no effective therapeutic options. Our laboratory has previously reported the development of genetically engineered DIPG mouse models using the RCAS/tv-a system, including a model driven by P...

Full description

Bibliographic Details
Main Authors: Halvorson, Kyle G., Barton, Kelly L., Schroeder, Kristin, Misuraca, Katherine L., Hoeman, Christine, Chung, Alex, Crabtree, Donna M., Cordero, Francisco J., Singh, Raj, Spasojevic, Ivan, Berlow, Noah, Pal, Ranadip, Becher, Oren J.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352073/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352073/

Similar Items