Exome Sequencing of Bilateral Testicular Germ Cell Tumors Suggests Independent Development Lineages12
Intratubular germ cell neoplasia, the precursor of testicular germ cell tumors (TGCTs), is hypothesized to arise during embryogenesis from developmentally arrested primordial germ cells (PGCs) or gonocytes. In early embryonal life, the PGCs migrate from the yolk sac to the dorsal body wall where the...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Neoplasia Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351294/ |