A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets

A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets

MYB activation is proposed to underlie development of adenoid cystic cancer (ACC), an aggressive salivary gland tumor with no effective systemic treatments. To discover druggable targets for ACC, we performed global mRNA/miRNA analyses of 12 ACC with matched normal tissues, and compared these data w...

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Bibliographic Details
Main Authors: Gao, Ruli, Cao, Chunxia, Zhang, Min, Lopez, Maria-Cecilia, Yan, Yuanqing, Chen, Zirong, Mitani, Yoshitsugu, Zhang, Li, Zajac-Kaye, Maria, Liu, Bin, Wu, Lizi, Renne, Rolf, Baker, Henry V., El-Naggar, Adel, Kaye, Frederic J.
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350357/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350357/

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