Protective effects of curcumin in APPswe transfected SH-SY5Y cells★

The APPswe plasmid was transfected into the neuroblastoma cell line SH-SY5Y to establish a cell model of Alzheimer's disease. Graded concentration and time course experiments demonstrate that curcumin significantly upregulates phosphatidylinositol 3-kinase (PI3K), Akt, nuclear factor E2-related...

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Bibliographic Details
Main Authors: Yin, Wenke, Zhang, Xiong, Li, Yu
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350125/