Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis

Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis

Metabolic manipulation of host cells by intracellular pathogens is currently recognized to play an important role in the pathology of infection. Nevertheless, little information is available regarding mitochondrial energy metabolism in Leishmania infected macrophages. Here, we demonstrate that durin...

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Bibliographic Details
Main Authors: Moreira, Diana, Rodrigues, Vasco, Abengozar, Maria, Rivas, Luis, Rial, Eduardo, Laforge, Mireille, Li, Xiaoling, Foretz, Marc, Viollet, Benoit, Estaquier, Jérôme, Cordeiro da Silva, Anabela, Silvestre, Ricardo
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349736/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349736/

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