The gap junction blocker carbenoxolone enhances propofol and sevoflurane-induced loss of consciousness☆
General anesthetics induce loss of consciousness by inhibiting ascending arousal pathways, and they interfere with gap junction electrical coupling. The present study aimed to determine whether inhibition of gap junction-mediated signaling could influence general anesthetic-induced loss of conscious...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Medknow Publications & Media Pvt Ltd
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348993/ |