Competition between cap and basal actin fiber orientation in cells subjected to contact guidance and cyclic strain

In vivo, adhesive cells continuously respond to a complex range of physical cues coming from the surrounding microenvironment by remodeling their cytoskeleton. Topographical and mechanical cues applied separately have been shown to affect the orientation of the actin stress fibers. Here we investiga...

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Bibliographic Details
Main Authors: Tamiello, Chiara, Bouten, Carlijn V. C., Baaijens, Frank P. T.
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348627/