Imaging regulatory T cell dynamics and suppression of T cell priming mediated by CTLA4

Foxp3+ regulatory T cells (Tregs) maintain immune homeostasis through mechanisms that remain incompletely defined. Here, by two-photon imaging, we examine the cellular dynamics of endogenous Tregs. Tregs are identified as two non-overlapping populations in the T-zone and follicular regions of the ly...

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Bibliographic Details
Main Authors: Matheu, Melanie P., Othy, Shivashankar, Greenberg, Milton L., Dong, Tobias X., Schuijs, Martijn, Deswarte, Kim, Hammad, Hamida, Lambrecht, Bart N., Parker, Ian, Cahalan, Michael D.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347855/