Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes

In mammals, the testis-specific bromodomain and extra terminal (BET) protein BRDT is essential for spermatogenesis. In Drosophila, it was recently reported that the tBRD-1 protein is similarly required for male fertility. Interestingly, however, tBRD-1 has two conserved bromodomains in its N-terminu...

Full description

Bibliographic Details
Main Authors: Kimura, Shuhei, Loppin, Benjamin
Format: Online
Language:English
Published: The Royal Society 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345279/