Autophagy regulates tissue overgrowth in a context-dependent manner
Autophagy is a catabolic process that has been implicated as both a tumor suppressor and in tumor progression. Here, we investigate this dichotomy in cancer biology by studying the influence of altered autophagy in Drosophila models of tissue overgrowth. We find that the impact of altered autophagy...
Main Authors: | Pérez, Ernesto, Das, Gautam, Bergmann, Andreas, Baehrecke, Eric H. |
---|---|
Format: | Online |
Language: | English |
Published: |
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345156/ |
Similar Items
-
Autophagy, cell death, and cancer
by: Lin, Lin, et al.
Published: (2015) -
Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner
by: Bejarano, Eloy, et al.
Published: (2012) -
Current questions and possible controversies in autophagy
by: Lindqvist, L M, et al.
Published: (2015) -
Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent
by: Morgan, Michael J, et al.
Published: (2014) -
Activated FGFR3 contributes to cancer in a context-dependent manner
Published: (2011)