Exogenous IL-2 Controls the Balance in Th1, Th17, and Treg Cell Distribution in Patients with Progressive Rheumatoid Arthritis Treated with TNF-Alpha Inhibitors
Interleukin-2 (IL-2) has been suggested to control Treg/Th17 balance. Recently, we reported a relationship of rheumatoid arthritis (RA) activity/progression with irreversible systemic Treg and Th1 defects including serum IL-2 shortage. Herein, we explore the role of in vitro stimulation with rIL-2 i...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer US
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344954/ |