Identification of Effective Subdominant Anti-HIV-1 CD8+ T Cells Within Entire Post-infection and Post-vaccination Immune Responses

Identification of Effective Subdominant Anti-HIV-1 CD8+ T Cells Within Entire Post-infection and Post-vaccination Immune Responses

Defining the components of an HIV immunogen that could induce effective CD8+ T cell responses is critical to vaccine development. We addressed this question by investigating the viral targets of CD8+ T cells that potently inhibit HIV replication in vitro, as this is highly predictive of virus contro...

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Bibliographic Details
Main Authors: Hancock, Gemma, Yang, Hongbing, Yorke, Elisabeth, Wainwright, Emma, Bourne, Victoria, Frisbee, Alyse, Payne, Tamika L., Berrong, Mark, Ferrari, Guido, Chopera, Denis, Hanke, Tomas, Mothe, Beatriz, Brander, Christian, McElrath, M. Juliana, McMichael, Andrew, Goonetilleke, Nilu, Tomaras, Georgia D., Frahm, Nicole, Dorrell, Lucy
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344337/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344337/

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