Protein Sectors: Statistical Coupling Analysis versus Conservation
Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed “sectors”. The method applies spectral analysis to a matrix obtained by combining correlation information with sequence conservation. It has been...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344308/ |