Human leukocyte telomere length is associated with DNA methylation levels in multiple subtelomeric and imprinted loci

In humans, leukocyte telomere length (LTL) is positively correlated with lifespan, and shorter LTL is associated with increased risk of age-related disease. In this study we tested for association between telomere length and methylated cytosine levels. Measurements of mean telomere length and DNA me...

Full description

Bibliographic Details
Main Authors: Buxton, Jessica L., Suderman, Matthew, Pappas, Jane J., Borghol, Nada, McArdle, Wendy, Blakemore, Alexandra I. F., Hertzman, Clyde, Power, Christine, Szyf, Moshe, Pembrey, Marcus
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344300/