Targeting zinc homeostasis to combat Aspergillus fumigatus infections

Aspergillus fumigatus is able to invade and grow in the lungs of immunosuppressed individuals and causes invasive pulmonary aspergillosis. The concentration of free zinc in living tissues is much lower than that required for optimal fungal growth in vitro because most of it is tightly bound to prote...

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Bibliographic Details
Main Authors: Vicentefranqueira, Rocío, Amich, Jorge, Laskaris, Paris, Ibrahim-Granet, Oumaima, Latgé, Jean P., Toledo, Héctor, Leal, Fernando, Calera, José A.
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343018/