Myelin Abnormalities in the Optic and Sciatic Nerves in Mice With GM1-Gangliosidosis

GM1-gangliosidosis is a glycosphingolipid lysosomal storage disease involving accumulation of GM1 and its asialo form (GA1) primarily in the brain. Thin-layer chromatography and X-ray diffraction were used to analyze the lipid content/composition and the myelin structure of the optic and sciatic ner...

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Bibliographic Details
Main Authors: Heinecke, Karie A., Luoma, Adrienne, d’Azzo, Alessandra, Kirschner, Daniel A., Seyfried, Thomas N.
Format: Online
Language:English
Published: SAGE Publications 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342369/