The “virgin birth”, polyploidy, and the origin of cancer

Recently, it has become clear that the complexity of cancer biology cannot fully be explained by somatic mutation and clonal selection. Meanwhile, data have accumulated on how cancer stem cells or stemloids bestow immortality on tumour cells and how reversible polyploidy is involved. Most recently,...

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Bibliographic Details
Main Authors: Erenpreisa, Jekaterina, Salmina, Kristine, Huna, Anda, Jackson, Thomas R., Vazquez-Martin, Alejandro, Cragg, Mark S.
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341460/