Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience

We reviewed the surgical treatment and outcomes of 13 patients with pelvic osteosarcoma treated in our centre in the past decade. The study sample included 9 males and 4 females with a mean age of 28.1 years. Four patients had ileal lesions, five had acetabulum lesions, one had a ischiopubis lesion,...

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Main Authors:	Ariff, MS, Zulmi, W, Faisham, WI, Nor Azman, MZ, Nawaz, AH
Format:	Online
Language:	English
Published:	Malaysian Orthopaedic Association 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341051/

id	pubmed-4341051
recordtype	oai_dc
spelling	pubmed-43410512015-02-26 Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience Ariff, MS Zulmi, W Faisham, WI Nor Azman, MZ Nawaz, AH Research Article We reviewed the surgical treatment and outcomes of 13 patients with pelvic osteosarcoma treated in our centre in the past decade. The study sample included 9 males and 4 females with a mean age of 28.1 years. Four patients had ileal lesions, five had acetabulum lesions, one had a ischiopubis lesion, and three had involvement of the whole hemipelvis. Seven patients presented with distant metastases at diagnosis. Limb salvage was performed in 6 patients and amputation in 7. In 60% of cases in the limb salvage surgery group, we attempted wide resection with positive microscopic margin compared to only 16.7% in the amputation group. Local recurrence was higher in the limb salvage group. Overall survival was 18 months for mean follow up of 14.8 months. Median survival was 19 months in the limb salvage group compared to 9 months in amputation group. The outcome of surgical treatment of pelvic osteosarcoma remains poor despite advancements in musculoskeletal oncology treatment. Malaysian Orthopaedic Association 2013-03 /pmc/articles/PMC4341051/ /pubmed/25722809 http://dx.doi.org/10.5704/MOJ.1303.018 Text en Copyright © 2014, Malaysian Orthopaedic Journal This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Ariff, MS Zulmi, W Faisham, WI Nor Azman, MZ Nawaz, AH
spellingShingle	Ariff, MS Zulmi, W Faisham, WI Nor Azman, MZ Nawaz, AH Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience
author_facet	Ariff, MS Zulmi, W Faisham, WI Nor Azman, MZ Nawaz, AH
author_sort	Ariff, MS
title	Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience
title_short	Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience
title_full	Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience
title_fullStr	Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience
title_full_unstemmed	Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience
title_sort	outcome of surgical treatment of pelvic osteosarcoma: hospital universiti sains malaysia experience
description	We reviewed the surgical treatment and outcomes of 13 patients with pelvic osteosarcoma treated in our centre in the past decade. The study sample included 9 males and 4 females with a mean age of 28.1 years. Four patients had ileal lesions, five had acetabulum lesions, one had a ischiopubis lesion, and three had involvement of the whole hemipelvis. Seven patients presented with distant metastases at diagnosis. Limb salvage was performed in 6 patients and amputation in 7. In 60% of cases in the limb salvage surgery group, we attempted wide resection with positive microscopic margin compared to only 16.7% in the amputation group. Local recurrence was higher in the limb salvage group. Overall survival was 18 months for mean follow up of 14.8 months. Median survival was 19 months in the limb salvage group compared to 9 months in amputation group. The outcome of surgical treatment of pelvic osteosarcoma remains poor despite advancements in musculoskeletal oncology treatment.
publisher	Malaysian Orthopaedic Association
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341051/
_version_	1613192752019800064

Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience

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