Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆

Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆

A contusive model of spinal cord injury at spinal segment T8-9 was established in rats. Huantiao (GB30) and Huatuojiaji (Ex-B05) were punctured with needles, and endogenous neural stem cells were labeled with 5-bromo-2’-deoxyuridine (BrdU) and NG2. Double immunofluorescence staining showed that elec...

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Main Authors: Wu, Haiying, Hu, Min, Yuan, Dekai, Wang, Yunhui, Wang, Jing, Li, Tao, Qian, Chuanyun, Yu, Hualin
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340030/
id pubmed-4340030
recordtype oai_dc
spelling pubmed-43400302015-02-26 Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆ Wu, Haiying Hu, Min Yuan, Dekai Wu, Haiying Wang, Yunhui Wang, Jing Li, Tao Qian, Chuanyun Yu, Hualin Research and Report: Acupuncture and Moxibustion and Neural Regeneration A contusive model of spinal cord injury at spinal segment T8-9 was established in rats. Huantiao (GB30) and Huatuojiaji (Ex-B05) were punctured with needles, and endogenous neural stem cells were labeled with 5-bromo-2’-deoxyuridine (BrdU) and NG2. Double immunofluorescence staining showed that electroacupuncture markedly increased the numbers of BrdU+/NG2+ cells at spinal cord tissue 15 mm away from the injury center in the rostral and caudal directions. The results suggest that electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in rats with spinal cord injury. Medknow Publications & Media Pvt Ltd 2012-05-25 /pmc/articles/PMC4340030/ /pubmed/25722706 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.15.003 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Wu, Haiying
Hu, Min
Yuan, Dekai
Wu, Haiying
Wang, Yunhui
Wang, Jing
Li, Tao
Qian, Chuanyun
Yu, Hualin
spellingShingle Wu, Haiying
Hu, Min
Yuan, Dekai
Wu, Haiying
Wang, Yunhui
Wang, Jing
Li, Tao
Qian, Chuanyun
Yu, Hualin
Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆
author_facet Wu, Haiying
Hu, Min
Yuan, Dekai
Wu, Haiying
Wang, Yunhui
Wang, Jing
Li, Tao
Qian, Chuanyun
Yu, Hualin
author_sort Wu, Haiying
title Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆
title_short Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆
title_full Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆
title_fullStr Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆
title_full_unstemmed Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆
title_sort electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆
description A contusive model of spinal cord injury at spinal segment T8-9 was established in rats. Huantiao (GB30) and Huatuojiaji (Ex-B05) were punctured with needles, and endogenous neural stem cells were labeled with 5-bromo-2’-deoxyuridine (BrdU) and NG2. Double immunofluorescence staining showed that electroacupuncture markedly increased the numbers of BrdU+/NG2+ cells at spinal cord tissue 15 mm away from the injury center in the rostral and caudal directions. The results suggest that electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in rats with spinal cord injury.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340030/
_version_ 1613192389656051712

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