A Comparative Evaluation of a Novel Vaccine in APP/PS1 Mouse Models of Alzheimer's Disease

Immunization against amyloid-beta-peptide (Aβ) has been widely investigated as a potential immunotherapeutic approach for Alzheimer's disease (AD). With the aim of developing an active immunogenic vaccine without need of coadjuvant modification for human trials and therefore avoiding such side...

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Bibliographic Details
Main Authors: Carrera, Iván, Etcheverría, Ignacio, Fernández-Novoa, Lucía, Lombardi, Valter Ruggero Maria, Lakshmana, Madepalli Krishnappa, Cacabelos, Ramón, Vigo, Carmen
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339718/