Synthesis of an anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell line

Synthesis of an anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell line

Anthraquinones are an important class of naturally occurring biologically active compounds. In this study, anthraquinone derivative 1,3-dihydroxy-9,10-anthraquinone-2- carboxylic acid (DHAQC) (2) was synthesized with 32% yield through the Friedel–Crafts condensation reaction. The mechanisms of cytot...

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Bibliographic Details
Main Authors: Yeap, SweeKeong, Akhtar, Muhammad Nadeem, Lim, Kian Lam, Abu, Nadiah, Ho, Wan Yong, Zareen, Seema, Roohani, Kiarash, Ky, Huynh, Tan, Sheau Wei, Lajis, Nordin, Alitheen, Noorjahan Banu
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338775/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338775/

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