Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution

The ryanodine receptors (RyRs) are high-conductance intracellular Ca2+ channels that play a pivotal role in the excitation-contraction coupling of skeletal and cardiac muscles. RyRs are the largest known ion channels, with a homotetrameric organization and approximately 5000 residues in each protome...

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Bibliographic Details
Main Authors: Yan, Zhen, Bai, Xiaochen, Yan, Chuangye, Wu, Jianping, Li, Zhangqiang, Xie, Tian, Peng, Wei, Yin, Changcheng, Li, Xueming, Scheres, Sjors H.W., Shi, Yigong, Yan, Nieng
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338550/