Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution
The ryanodine receptors (RyRs) are high-conductance intracellular Ca2+ channels that play a pivotal role in the excitation-contraction coupling of skeletal and cardiac muscles. RyRs are the largest known ion channels, with a homotetrameric organization and approximately 5000 residues in each protome...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338550/ |