Enrichment of CD56dimKIR+CD57+ highly cytotoxic NK cells in tumor infiltrated lymph nodes of melanoma patients

Enrichment of CD56dimKIR+CD57+ highly cytotoxic NK cells in tumor infiltrated lymph nodes of melanoma patients

An important checkpoint in the progression of melanoma is the metastasis to lymph nodes. Here, to investigate the role of lymph node NK cells in disease progression, we analyze frequency, phenotype and functions of NK cells from tumor-infiltrated (TILN) and tumor-free ipsilateral lymph nodes (TFLN)...

Full description

Bibliographic Details
Main Authors: Ali, Talib Hassan, Pisanti, Simona, Ciaglia, Elena, Mortarini, Roberta, Anichini, Andrea, Garofalo, Cinzia, Tallerico, Rossana, Santinami, Mario, Gulletta, Elio, Ietto, Caterina, Galgani, Mario, Matarese, Giuseppe, Bifulco, Maurizio, Ferrone, Soldano, Colucci, Francesco, Moretta, Alessandro, Kärre, Klas, Carbone, Ennio
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338526/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338526/

Similar Items