MutT from the fish pathogen Aliivibrio salmonicida is a cold-active nucleotide-pool sanitization enzyme with unexpectedly high thermostability
•MutT from A. salmonicida and V. cholera are functional Nudix hydrolases.•A. salmonicida MutT (AsMutT) is cold active with unexpected high thermostability.•AsMutT has lower activation energy than V. cholera MutT (VcMutT).•The crystal structure of VcMutT is determined to 2.42 Å.•Both enzymes represen...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338371/ |