Activation of Human γδ T Cells by Cytosolic Interactions of BTN3A1 with Soluble Phosphoantigens and the Cytoskeletal Adaptor Periplakin

The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A1 controls activation of human Vγ9/Vδ2 T cells by direct or indirect presentation of self and nonself phosphoant...

Full description

Bibliographic Details
Main Authors: Rhodes, David A., Chen, Hung-Chang, Price, Amanda J., Keeble, Anthony H., Davey, Martin S., James, Leo C., Eberl, Matthias, Trowsdale, John
Format: Online
Language:English
Published: AAI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337483/