Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes

Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes

The RNase III enzyme DICER generates both microRNAs (miRNAs) and endogenous short interfering RNAs (endo-siRNAs). Both small RNA species silence gene expression post-transcriptionally in association with the ARGONAUTE (AGO) family of proteins. In mammals, there are four AGO proteins (AGO1-4), of whi...

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Bibliographic Details
Main Authors: Stein, Paula, Rozhkov, Nikolay V., Li, Fan, Cárdenas, Fabián L., Davydenk, Olga, Vandivier, Lee E., Gregory, Brian D., Hannon, Gregory J., Schultz, Richard M.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335007/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335007/

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