Defective Differentiation of Adipose Precursor Cells from Lipodystrophic Mice Lacking Perilipin 1

Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and hydrolysis in adipocytes. Plin1 defect leads to low adiposity in mice and partial lipodystrophy in human. This study investigated the roles of Plin1 in adipocyte differentiation. Plin1 null (-/-) mice...

Full description

Bibliographic Details
Main Authors: Lyu, Ying, Su, Xueying, Deng, Jingna, Liu, Shangxin, Zou, Liangqiang, Zhao, Xiaojing, Wei, Suning, Geng, Bin, Xu, Guoheng
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335001/