The G-protein Alpha Subunit Gsα Is A Tumor Suppressor In Sonic Hedgehog-driven Medulloblastoma

The G-protein Alpha Subunit Gsα Is A Tumor Suppressor In Sonic Hedgehog-driven Medulloblastoma

Medulloblastoma, the most common malignant childhood brain tumor, exhibits distinct molecular subtypes and cellular origins. Genetic alterations driving medulloblastoma initiation and progression remain poorly understood. Herein, we identify GNAS, encoding the G-protein Gsα, as a potent tumor suppre...

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Bibliographic Details
Main Authors: He, Xuelian, Zhang, Liguo, Chen, Ying, Remke, Marc, Shih, David, Lu, Fanghui, Wang, Haibo, Deng, Yaqi, Yu, Yang, Xia, Yong, Wu, Xiaochong, Ramaswamy, Vijay, Hu, Tom, Wang, Fan, Zhou, Wenhao, Burns, Dennis K., Kim, Se Hoon, Kool, Marcel, Pfister, Stefan M., Weinstein, Lee S., Pomeroy, Scott L., Gilbertson, Richard J., Rubin, Joshua B., Hou, Yiping, Wechsler-Reya, Robert, Taylor, Michael D., Lu, Q. Richard
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334261/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334261/

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