Evaluating the safety and efficacy of axitinib in the treatment of advanced renal cell carcinoma

Axitinib is a tyrosine kinase inhibitor of vascular endothelial growth factor receptor, platelet-derived growth factor receptor-α, and c-kit. Phase I studies demonstrated 5 mg twice daily as the recommended starting dose with notable effects seen in renal cell carcinoma, an observation confirmed in...

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Bibliographic Details
Main Authors: Gunnarsson, Orvar, Pfanzelter, Nicklas R, Cohen, Roger B, Keefe, Stephen M
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334173/