Evaluating the safety and efficacy of axitinib in the treatment of advanced renal cell carcinoma
Axitinib is a tyrosine kinase inhibitor of vascular endothelial growth factor receptor, platelet-derived growth factor receptor-α, and c-kit. Phase I studies demonstrated 5 mg twice daily as the recommended starting dose with notable effects seen in renal cell carcinoma, an observation confirmed in...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334173/ |